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In a newborn suspected of having a tracheo-esophageal fistula, which symptom would be indicative?

  1. Drooling and diarrhea

  2. Increased mucus production and oral secretions

  3. Air distention in the stomach and vomiting

  4. Persistent cyanosis and visible peristaltic waves

The correct answer is: Increased mucus production and oral secretions

In a newborn suspected of having a tracheo-esophageal fistula, the presence of increased mucus production and oral secretions is a key indicative symptom. This occurs because the abnormal connection between the trachea and esophagus can lead to aspiration of oral secretions into the lungs, causing an accumulation of mucus. Newborns are particularly susceptible to this due to their underdeveloped swallowing mechanisms and increased secretions. The condition can also lead to difficulty in managing oral secretions, as they may not be able to effectively swallow or clear these secretions. The increased oral secretions, often described as copious, serve as a sign that the structural anomaly is impacting normal physiological function. Other symptoms associated with tracheo-esophageal fistula can include respiratory distress, feeding difficulties, and potentially gastrointestinal symptoms, but those specific to excessive secretions highlight the pathophysiological processes at play in tracheo-esophageal fistulas.